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Licensed Unlicensed Requires Authentication Published by De Gruyter February 25, 2022

CSF-interleukin 6 for early diagnosis of ventriculitis in a broad intensive care setting

  • Sylvia Mink EMAIL logo , Wolfgang List , Patrick Reimann ORCID logo and Peter Fraunberger

Corresponding author: Sylvia Mink, Medical Central Laboratories, Carinagasse 41, 6800 Feldkirch, Vorarlberg, Austria; and Private University of the Principality of Liechtenstein, Triesen, Principality of Liechtenstein, Phone: +43 5522 3480 340, Fax: +43 5522 3480 9340, E-mail:

  1. Research funding: None declared.

  2. Author contributions: All authors have accepted responsibility for the entire content of this manuscript and approved its submission.

  3. Competing interests: Authors state no conflict of interest.

  4. Informed consent: Not applicable.

  5. Ethical approval: The local Institutional Review Board deemed the study exempt from review.

References

1. Hasbun, R. Healthcare-associated ventriculitis: current and emerging diagnostic and treatment strategies. Expert Rev Anti-infect Ther 2021;19:993–9. https://doi.org/10.1080/14787210.2021.1866544.Search in Google Scholar PubMed

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3. Lunardi, LW, Zimmer, ER, dos Santos, SC, Merzoni, J, Portela, LV, Stefani, MA. Cell index in the diagnosis of external ventricular drain-related infections. World Neurosurg 2017;106:504–8. https://doi.org/10.1016/j.wneu.2017.07.012.Search in Google Scholar PubMed

4. Takahashi, W, Nakada, T, Abe, R, Tanaka, K, Matsumura, Y, Oda, S. Usefulness of interleukin 6 levels in the cerebrospinal fluid for the diagnosis of bacterial meningitis. J Crit Care 2014;29:693.e1–6. https://doi.org/10.1016/j.jcrc.2014.02.020.Search in Google Scholar PubMed

5. Lenski, M, Biczok, A, Neufischer, K, Tonn, J-C, Briegel, J, Thon, N. Significance of cerebrospinal fluid inflammatory markers for diagnosing external ventricular drain-associated ventriculitis in patients with severe traumatic brain injury. Neurosurg Focus 2019;47:E15. https://doi.org/10.3171/2019.8.focus19407.Search in Google Scholar

Received: 2021-11-25
Accepted: 2022-02-15
Published Online: 2022-02-25
Published in Print: 2022-05-25

© 2022 Walter de Gruyter GmbH, Berlin/Boston

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